Symbol
Name
ID

Cd44
CD44 antigen
MGI:88338

Phenotype annotations related to hematopoietic system

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Mouse Phenotypes

hematopoietic system phenotype

decreased activation-induced cell death of T cells

abnormal osteoclast differentiation

abnormal leukocyte migration

impaired leukocyte tethering or rolling

abnormal leukocyte adhesion

decreased T cell proliferation

impaired macrophage phagocytosis

abnormal definitive hematopoiesis

decreased mast cell number

decreased mast cell histamine storage

decreased central memory CD4-positive, alpha-beta T cell number

decreased effector memory CD4-positive, alpha-beta T cell number

decreased CD4-positive, alpha-beta T cell number

decreased central memory CD8 positive, alpha-beta T cell number

decreased CD8-positive, alpha-beta T cell number

decreased alpha-beta T cell number

abnormal CD4-positive, alpha beta T cell morphology

abnormal CD8-positive, alpha beta T cell morphology

abnormal neutrophil physiology

impaired neutrophil recruitment

impaired natural killer cell mediated cytotoxicity

abnormal CD4-positive, alpha-beta T cell physiology

abnormal T-helper 1 physiology

abnormal T-helper 2 physiology

Availability

Mouse Genotype

Cd44^M1Btlr/Cd44^M1Btlr

Cd44^tm1.1Ugu/Cd44^tm1.1Ugu

Cd44^tm1Hbg/Cd44^tm1Hbg

Cd44^tm1Mak/Cd44^tm1Mak

Cd44^tm1Ugu/Cd44^tm1Ugu

Cd44^tm2.1Ugu/Cd44^tm2.1Ugu

Cd44^tm2Kmz/Cd44^tm2Kmz

Cd44^tm1Mak/Cd44⁺

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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